HerbMate Library

Fo-Ti (He Shou Wu)

Polygonum multiflorum (syn. Reynoutria multiflora)
rootlongevityhairliverhigh-cautiontraditional-chinese

Fo-ti (He Shou Wu) is a traditional Chinese root used in longevity and hair-support formulas. However, it has a well-known safety concern: fo-ti has been linked to liver injury in case reports, especially with certain preparations or high-dose/long-term use. If used at all, it should be used cautiously, sourced carefully, and not treated as a casual daily supplement.

Key Benefits

Common Issues It May Help With

How To Use (Simple)

Taste / Notes

Earthy, slightly sweet, bitter (varies by preparation).

Evidence Level

Traditional use is strong; modern clinical evidence for marketed benefits is limited. Safety concerns around liver toxicity are well documented in case literature.

Cautions

HIGH CAUTION: Potential liver toxicity. Avoid if you have liver disease, elevated liver enzymes, heavy alcohol use, or are taking hepatotoxic medications. Avoid during pregnancy/breastfeeding. Do not use in children. Stop immediately if signs of liver stress appear.

Interactions

Avoid with hepatotoxic medications (e.g., high-dose acetaminophen, some antifungals, certain anticonvulsants) and heavy alcohol use If on immunosuppressants or complex medication regimens, consult a clinician before any use May interact unpredictably with other herbal ‘tonics’—avoid stacking multiple products

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