HerbMate Library

Wild Lettuce

Lactuca virosa
herbsleepcalmpain-supporthigh-cautionsedating

Wild lettuce is a traditional herb sometimes used for relaxation and sleep support. It has a long folk reputation, but effects can be unpredictable and product quality varies. Because it may be sedating and can interact with other sedatives, it’s a ‘use cautiously’ herb rather than a casual daily tea for everyone.

Key Benefits

Common Issues It May Help With

How To Use (Simple)

Taste / Notes

Very bitter, resinous, ‘green’ and sharp.

Evidence Level

Traditional use is common; modern clinical evidence is limited and inconsistent. Benefits are highly product- and person-dependent.

Cautions

HIGH CAUTION: May cause drowsiness, dizziness, nausea, or headache. Do not drive or operate machinery after use. Avoid during pregnancy/breastfeeding. Avoid in children. Use caution if you have glaucoma or prostate urinary retention concerns (theoretical). Stop if you experience palpitations, severe dizziness, or allergic symptoms.

Interactions

Additive sedation with alcohol, benzodiazepines, sleep medications, antihistamines, opioids, or other sedating herbs (e.g., valerian, kava) May increase dizziness when combined with blood pressure medications (additive hypotension in some people) If on psychiatric medications, consult a clinician before use due to limited safety data

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